2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W552133
    Propyl linoleate 38433-95-3 98.05%
    Propyl linoleate is an ester product.
    Propyl linoleate
  • HY-W552702
    Tyrosinase-IN-29 408335-66-0 98%
    Tyrosinase-IN-29 (compound 5c) is a potent inhibitor of tyrosinase abTYR (IC50: 6.11 μM). Tyrosinase-IN-29 can be used to further study the inhibition of skin hyperpigmentation.
    Tyrosinase-IN-29
  • HY-W554410
    Methyl 8-methylnonanoate 5129-54-4 98%
    Methyl 8-methylnonanoate is an ester product.
    Methyl 8-methylnonanoate
  • HY-W554893
    Behenate sodium 5331-77-1 99.85%
    Behenate (sodium) is an ester product.
    Behenate sodium
  • HY-W555010
    Phosphoenolpyruvic acid monosodium 53823-68-0 98%
    Phosphoenolpyruvic acid (Phosphoenolpyruvate) monosodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid monosodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid monosodium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid monosodium
  • HY-W556168
    Ethyl docosanoate 5908-87-2 98%
    Ethyl docosanoate (Ethyl behenate; Behenic acid ethyl ester) is an ester product.
    Ethyl docosanoate
  • HY-W564704
    (p-Hydroxybenzyl)malonic acid 90844-16-9 98%
    (p-Hydroxybenzyl)malonic acid is a hydroxyphenyl derivative capable of inhibiting insulin-induced lipogenesis in rat adipocytes with an IC50 value of 3.8 μM.
    (p-Hydroxybenzyl)malonic acid
  • HY-W585339
    BODIPY 505/515 PS ammonium 1246355-65-6 98%
    BODIPY?505/515 PS ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    BODIPY 505/515 PS ammonium
  • HY-W585353
    BODIPY 505/515 PE 1246355-64-5 98%
    BODIPY?505/515 PE is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    BODIPY 505/515 PE
  • HY-W585399
    BODIPY 505/515 Lyso PA 1246355-62-3 98%
    BODIPY?505/515 Lyso PA is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
    BODIPY 505/515 Lyso PA
  • HY-W585809
    1,3-Distearoyl-2-chloropropanediol 26787-56-4 98%
    1,3-Distearoyl-2-chloropropanediol (2-Chloropropane-1,3-diyl distearate) is an ester product.
    1,3-Distearoyl-2-chloropropanediol
  • HY-W585873
    Bupivacaine N-oxide hydrochloride 1796927-05-3 98%
    Bupivacaine N-oxide hydrochloride is a metabolite of Bupivacaine (HY-B0405). Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain.
    Bupivacaine N-oxide hydrochloride
  • HY-W585917
    Bisphenol F bis(2-chloro-1-propanol) ether 374772-79-9 98%
    Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) is an androgen receptor antagonist with a human IC50 of 18 μM. Bisphenol F bis(2-chloro-1-propanol) ether binds to the androgen receptor. Bisphenol F bis(2-chloro-1-propanol) ether (BFDGE·2HCl) can be used for research on hormonal activity.
    Bisphenol F bis(2-chloro-1-propanol) ether
  • HY-W585935
    Glycidyl oleate 5431-33-4 98%
    Glycidyl oleate (Oleic acid glycidyl ester) is an ester product.
    Glycidyl oleate
  • HY-W585948
    1-Palmitoyl-2-oleoyl-rac-glycerol 3123-73-7 98%
    1-Palmitoyl-2-oleoyl-rac-glycerol is a diacylglycerol containing Palmitic acid (HY-N0830) and Oleic acid (HY-N1446).
    1-Palmitoyl-2-oleoyl-rac-glycerol
  • HY-W587411
    2Carboxy-MMHP 82975-93-7 98%
    Mono[2-(carboxymethyl)hexyl] phthalate (MCHP) is a metabolite of Di-(2-ethylhexyl)phthalate (DEHP). DEH is an endocrine disrupting chemical that is widely used as the major plasticizer.
    2Carboxy-MMHP
  • HY-W587420
    1-Palmitoyl-3-chloropropanediol 30557-04-1 98%
    1-Palmitoyl-3-chloropropanediol (3-Chloro-1,2-propanediol 1-palmitate) is an ester product.
    1-Palmitoyl-3-chloropropanediol
  • HY-W587436
    N-Acetyl-S-(carbamoylethyl)-L-cysteine 81690-92-8 98%
    N-Acetyl-S-(2-carbamoylethyl) -L-cysteine is the urinary metabolite of acrylamide in humans, and its association with other diseases.
    N-Acetyl-S-(carbamoylethyl)-L-cysteine
  • HY-W587476
    3-Chloro-1,2-propanediol dilinoleate 74875-96-0 98%
    3-Chloro-1,2-propanediol dilinoleate is an ester product.
    3-Chloro-1,2-propanediol dilinoleate
  • HY-W587507
    1,2-Dilauroyl-3-chloropropanediol 1051389-99-1 98%
    1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
    1,2-Dilauroyl-3-chloropropanediol
Cat. No. Product Name / Synonyms Application Reactivity